Vitamin D3 and B12 supplementation in pregnancy

Vitamin B12 in Macrocytic Anæmia in Pregnancy

Vitamin C supplementation in pregnancy.

BACKGROUND Vitamin C supplementation may help reduce the risk of pregnancy complications like pre-eclampsia, intrauterine growth restriction and maternal anaemia. There is a need to evaluate the efficacy and safety of vitamin C supplementation in pregnancy. OBJECTIVES To evaluate the effects of vitamin C supplementation, alone or in combination with other separate supplements, on pregnancy ou...

Vitamin B12 Metabolism during Pregnancy and in Embryonic Mouse Models

Vitamin B(12) (cobalamin, Cbl) is required for cellular metabolism. It is an essential coenzyme in mammals for two reactions: the conversion of homocysteine to methionine by the enzyme methionine synthase and the conversion of methylmalonyl-CoA to succinyl-CoA by the enzyme methylmalonyl-CoA mutase. Symptoms of Cbl deficiency are hematological, neurological and cognitive, including megaloblasti...

Cobalt and Vitamin B12 Supplementation of Young Sheep

The efficacy of 4 treatments in maintaining adequate plasma and liver vitamin B lz (B,,) concentrations was compared in young sheep grazing a cobalt (Co)-deficient site in the south east of South Australia. The treatments were injections of Blz or an intraruminal glass pellet containing Co prior to weaning and at weaning intraruminal glass pellets or Co pellets. A liveweight and fleece weight r...

Vitamin B12 among Vegetarians: Status, Assessment and Supplementation

Cobalamin is an essential molecule for humans. It acts as a cofactor in one-carbon transfers through methylation and molecular rearrangement. These functions take place in fatty acid, amino acid and nucleic acid metabolic pathways. The deficiency of vitamin B12 is clinically manifested in the blood and nervous system where the cobalamin plays a key role in cell replication and in fatty acid met...